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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 4705Generated: October 25, 2026

L-Proline → 6-methoxy-3,4-dihydro-4-methyl-2H-1,4-benzodiazepine-2,5(1H)-dione

https://huagongshe.com/reaction/4705

Reaction equation

Participants

RoleNameHCIDCharge
ReactantL-ProlineHCID 145742—
Reactant(S)-1,2,3,11a-tetrahydro-6-methyl-5H-pyrrolo[2,1-c][1,4]benzodiazepine-5,11(10H)-dioneHCID 13891432—
Product6-methoxy-3,4-dihydro-4-methyl-2H-1,4-benzodiazepine-2,5(1H)-dioneHCID 21291977—

Reaction Steps

(S)-6-methyl-1,2,3,11a-tetrahydro-5H-pyrrolo (2,1-c) (1,4) benzodiazepine-5,11 (10H)-dione by reaction with L-proline. M.p. 207.6°-209.9° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04727153
Source datasetuspto-grants-1988_02
ORD IDord-5eae9c249c2f4d548c00c56de8b74d45
Source noteuspto-grants-1988_02