HuagongsheHuagongshe Chemistry Print Report · For research reference only
(S)-6-(2-hydroxy-2-methylpropyl)-6-phenyl-3-((S)-1-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)ethyl)-1,3-oxazinan-2-one → HCID 44476983, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (S)-6-(2-hydroxy-2-methylpropyl)-6-phenyl-3-((S)-1-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)ethyl)-1,3-oxazinan-2-one | HCID 59532385 | — |
| Reactant | 4-Bromo-1-(2-hydroxy-2-methylpropyl)-2(1H)-pyridinone | HCID 59635730 | — |
| Product | HCID 44476983 | HCID 44476983 | — |
Reaction Steps
The title compound was prepared from (S)-6-(2-hydroxy-2-methylpropyl)-6-phenyl-3-[(S)-1-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)ethyl]-1,3-oxazinan-2-one and 4-bromo-1-(2-hydroxy-2-methyl-propyl)-1H-pyridin-2-one following a procedure analogous to that described in Example 75. Mass spectrum (ESI+): m/z=519 [m+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08629138B2 |
| Source dataset | uspto-grants-2014_01 |
| ORD ID | ord-1718097c9d184ae499aa82a09240ec02 |
| Source note | uspto-grants-2014_01 |