HuagongsheHuagongshe Chemistry Print Report · For research reference only
(R)-2-methyl-propane-2-sulfinic acid [(S)-1-(4-bromo-3-methyl-phenyl)-ethyl]amide → (S)-1-(4-Bromo-3-methylphenyl)ethan-1-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (R)-2-methyl-propane-2-sulfinic acid [(S)-1-(4-bromo-3-methyl-phenyl)-ethyl]amide | HCID 58102400 | — |
| Reactant | 6-cyclopropyl-6-(2-hydroxy-2-methylpropyl)-3-((S)-1-(4-(1-methyl-2-oxo-1,2-dihydropyridin-4-yl)phenyl)ethyl)-1,3-oxazinan-2-one | HCID 59635673 | — |
| Product | (S)-1-(4-Bromo-3-methylphenyl)ethan-1-amine | HCID 58102381 | — |
Reaction Steps
The title compound was prepared from (R)-2-methyl-propane-2-sulfinic acid [(S)-1-(4-bromo-3-methyl-phenyl)-ethyl]amide following a procedure analogous to that described in Step 3 of Intermediate 1. LC-MS (Method 4): tR=3.56 min; Mass spectrum (ESI+): m/z=214/216 (Br) [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08629138B2 |
| Source dataset | uspto-grants-2014_01 |
| ORD ID | ord-562be0e5089d4e5a9d3fcc88821260b1 |
| Source note | uspto-grants-2014_01 |