HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triphosgene → 5-Bromo-2-isocyanatomethyl-1,3-dimethyl-benzene
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triphosgene | HCID 94429 | — |
| Reactant | (4-Bromo-2,6-dimethylphenyl)methanamine | HCID 39872008 | — |
| Reactant | 6-cyclopropyl-6-(2-hydroxy-2-methylpropyl)-3-((S)-1-(4-(1-methyl-2-oxo-1,2-dihydropyridin-4-yl)phenyl)ethyl)-1,3-oxazinan-2-one | HCID 59635673 | — |
| Product | 5-Bromo-2-isocyanatomethyl-1,3-dimethyl-benzene | HCID 58102394 | — |
Reaction Steps
The title compound was prepared from 4-bromo-2,6-dimethyl-benzylamine and triphosgene following a procedure analogous to that described in Step 4 of Intermediate 1. Mass spectrum (EI): m/z=239/241 (Br) [M]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08629138B2 |
| Source dataset | uspto-grants-2014_01 |
| ORD ID | ord-3344618a3cad4925933ba7bfb0497389 |
| Source note | uspto-grants-2014_01 |