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HRID470663

反应详情

EQUATION

反应方程式

HRID 470663 的结构方程式

REACTANTS

反应物

2
结构：CC1(C)CCC2(CC1)N1[C@H](c3ccccc3)[C@H](c3ccccc3)OC(=O)[C@H]1[C@H](c1cccc(Cl)c1F)[C@@]21C(=O)Nc2nc(Cl)ccc21
HCID86672583

未命名化合物

结构：N[C@H]1CC[C@H](CO)CC1
HCID178511560

未命名化合物

PRODUCTS

生成物

1
结构：CC1(C)CCC2(CC1)N([C@H](c1ccccc1)[C@@H](O)c1ccccc1)[C@@H](C(=O)N[C@H]1CC[C@H](CO)CC1)[C@H](c1cccc(Cl)c1F)C21C(=O)Nc2nc(Cl)ccc21
HCID178423624

未命名化合物

收率 83.4%

PROCEDURE

实验过程

The compound (260 mg, 0.39 mmol) obtained in Step 1 above and (trans-4-aminocyclohexyl)methanol (100 mg, 0.77 mmol) were used as starting materials and treated in the same way as in Step 2 of Example 1 to give 260 mg (83%) of the title compound as a pale yellow oil.

WORKUP

后处理

  1. additiontreated in the same way as in Step 2 of Example 1