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HRID470664

反应详情

EQUATION

反应方程式

HRID 470664 的结构方程式

REACTANTS

反应物

2
结构：NCC[C@H](O)CO
HCID55281176

未命名化合物

结构：CC1(C)CCC2(CC1)N1[C@H](c3ccccc3)[C@H](c3ccccc3)OC(=O)[C@H]1[C@H](c1cccc(Cl)c1F)[C@@]21C(=O)Nc2cc(Cl)ccc21
HCID70872025

未命名化合物

PRODUCTS

生成物

1
结构：CC1(C)CCC2(CC1)N([C@H](c1ccccc1)[C@@H](O)c1ccccc1)[C@@H](C(=O)NCC[C@H](O)CO)[C@H](c1cccc(Cl)c1F)C21C(=O)Nc2cc(Cl)ccc21
HCID68309385

未命名化合物

收率 55%

PROCEDURE

实验过程

The compound (1.01 g, 1.51 mmol) obtained in Step 1 of Example 1 and (2S)-4-aminobutane-1,2-diol (WO2007/011162) (475 mg, 4.53 mmol) were used as starting materials and treated in the same way as in Step 2 of Example 1 to give 644 mg (55%) of the title compound as a colorless amorphous solid.

WORKUP

后处理

  1. additiontreated in the same way as in Step 2 of Example 1