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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 471084Generated: October 30, 2026

Fumaric Acid → HCID 50913437, compound

https://huagongshe.com/reaction/471084

Reaction equation

Participants

RoleNameHCIDCharge
ReactantFumaric AcidHCID 444972—
ReactantHCID 49855236HCID 49855236—
SolventMethanolHCID 887—
ProductHCID 50913437HCID 50913437—

Reaction Steps

A solution of (R)-7-(2-(2-fluoro-5-((4-(2-isopropylthiazole-4-carbonyl)-1-oxa-4,9-diazaspiro[5.5]undecan-9-yl)methyl)phenethylamino)-1-hydroxyethyl)-4-hydroxybenzo[d]thiazol-2(3H)-one (13 mg) (example 47D, step a) and fumaric acid (2 mg) in methanol (0.75 mL) was stirred at RT for 7 days. The resulting white solid formed was isolated by filtration and dried under high vacuum to give the titled compound as a white solid. Yield 5 mg.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08629271B2
Source datasetuspto-grants-2014_01
ORD IDord-d7f92ee6ad5d4888a2aeffbee5751fe7
Source noteuspto-grants-2014_01