HuagongsheHuagongshe Chemistry Print Report · For research reference only
Fumaric Acid → HCID 50913437, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Fumaric Acid | HCID 444972 | — |
| Reactant | HCID 49855236 | HCID 49855236 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 50913437 | HCID 50913437 | — |
Reaction Steps
A solution of (R)-7-(2-(2-fluoro-5-((4-(2-isopropylthiazole-4-carbonyl)-1-oxa-4,9-diazaspiro[5.5]undecan-9-yl)methyl)phenethylamino)-1-hydroxyethyl)-4-hydroxybenzo[d]thiazol-2(3H)-one (13 mg) (example 47D, step a) and fumaric acid (2 mg) in methanol (0.75 mL) was stirred at RT for 7 days. The resulting white solid formed was isolated by filtration and dried under high vacuum to give the titled compound as a white solid. Yield 5 mg.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08629271B2 |
| Source dataset | uspto-grants-2014_01 |
| ORD ID | ord-d7f92ee6ad5d4888a2aeffbee5751fe7 |
| Source note | uspto-grants-2014_01 |