反应详情

A mixture consisting of 2.3 gm of 7,7-dimethyl-2-(4-benzyloxy-phenyl)-5H,7H-imidazo[4,5-h]isoquinoline-4,6-dione, 200 ml of methanol and 0.5 gm of 10% palladium-on-charcoal was hydrogenated at 50° C. at a hydrogen pressure of 5 atmospheres for 4 hours. The catalyst was then filtered off, the filtrate was evaporated to 50 ml and the precipitated crystals were suction-filtered off.

1. filtrationThe catalyst was then filtered off
2. customthe filtrate was evaporated to 50 ml
3. filtrationthe precipitated crystals were suction-filtered off