HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-(Acetylthio)-2-[(acetylthio)methyl]propanoic acid → 2-hydroxy-3-mercaptopropanoyl-L-lysine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-(Acetylthio)-2-[(acetylthio)methyl]propanoic acid | HCID 13145531 | — |
| Reactant | HCID 22805637 | HCID 22805637 | — |
| Reactant | 2-Acetoxy-3-(acetylthio)propanoic acid | HCID 23336183 | — |
| Reactant | Nalpha-[2-acetoxy-3-(acetylthio)propanoyl]-Nepsilon-tert.butyloxycarbonyl-L-lysine tert.butyl ester | HCID 86736713 | — |
| Product | 2-hydroxy-3-mercaptopropanoyl-L-lysine | HCID 86736712 | — |
Reaction Steps
By substituting 2-acetoxy-3-(acetylthio)propanoic acid for the 2-(acetylthiomethyl)-3-(acetylthio)propanoic acid in the procedure of Example 38 and then submitting the product to the procedures of Examples 39 and 40, Nα -[2-acetoxy-3-(acetylthio)propanoyl]-Nε -tert.butyloxycarbonyl-L-lysine tert.butyl ester, Nα -[2-acetoxy-3-(acetylthio)propanoyl]-L-lysine and Nα -(2-hydroxy-3-mercaptopropanoyl-L-lysine are obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04176235 |
| Source dataset | uspto-grants-1979_11 |
| ORD ID | ord-af0e3f842c9d4425a1e9851b048fb829 |
| Source note | uspto-grants-1979_11 |