Methyl iodide → 4,5-Dimethyl-2-(methylamino)thiophene-3-carbonitrile

HRID 471491Notes

Reaction equation

[NH2:1][C:2]1[S:3][C:4]([CH3:10])=[C:5]([CH3:9])[C:6]=1[C:7]#[N:8].[CH3:11]I>>[CH3:9][C:5]1[C:6]([C:7]#[N:8])=[C:2]([NH:1][CH3:11])[S:3][C:4]=1[CH3:10]

Participants

Reactant 2

HCID 6328Methyl iodide

HCID 2902362-Amino-4,5-dimethyl-thiophene-3-carbonitrile

Product 1

HCID 574569174,5-Dimethyl-2-(methylamino)thiophene-3-carbonitrile

Procedure

Prepared as in Example 21b from 2-amino-4,5-dimethylthiophene-3-carbonitrile and methyl iodide.

Sources & evidence

ORD record: ord-43cafaad480b4b6aa5ef08d1169ed581
Source dataset: uspto-grants-2014_01
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08633186B2

Reaction notes

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