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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 471502Generated: October 29, 2026

Dimethylamine → 2-Chloro-N,N-dimethylquinazolin-4-amine

https://huagongshe.com/reaction/471502

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDimethylamineHCID 674—
Reactant2,4-DichloroquinazolineHCID 252886—
Product2-Chloro-N,N-dimethylquinazolin-4-amineHCID 12684342—

Reaction Steps

Prepared as in Example 38 from 2,4-dichloroquinazoline and dimethylamine. 1H NMR (400 MHz, CDCl3) δ 3.42 (s, 6H), 7.42-7.39 (m, 1H), 7.72-7.70 (m, 1H), 7.79-7.77 (m, 1H), 8.03-8.01 (m, 1H). MS 208 (MH+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08633186B2
Source datasetuspto-grants-2014_01
ORD IDord-787481e5654b4b279bfaedf154789d7f
Source noteuspto-grants-2014_01