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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 471507Generated: October 30, 2026

Thiourea → HCID 25222914, compound

https://huagongshe.com/reaction/471507

Reaction equation

Participants

RoleNameHCIDCharge
ReactantThioureaHCID 2723790—
Reactant2-Chloro-N,N-dimethylquinazolin-4-amineHCID 12684342—
ProductHCID 25222914HCID 25222914—

Reaction Steps

Prepared as in Example 46 from 2-chloro-N,N-dimethylquinazolin-4-amine (Example 40) and thiourea. 1H NMR (400 MHz, DMSO-d6) δ 3.31 (s, 6H), 7.24-7.19 (m, 1H), 7.40-7.38 (m, 1H), 7.65-7.61 (m, 1H), 8.00 (d, J=8.0 Hz, 1H), 12.35 (s, 1H). MS 206 (MH+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08633186B2
Source datasetuspto-grants-2014_01
ORD IDord-cbea0977a40e4e11b95ca503dd6222b8
Source noteuspto-grants-2014_01