2-Amino-6-bromobenzonitrile → 2-Amino-6-(3-methylbut-2-en-2-yl)benzonitrile

HRID 471568Notes

Reaction equation

HRID 471568 reaction equation
[NH2:1][C:2]1[CH:9]=[CH:8][CH:7]=[C:6](Br)[C:3]=1[C:4]#[N:5].[CH3:11][C:12]([CH3:18])=[C:13](B(O)O)[CH3:14]>>[NH2:1][C:2]1[CH:9]=[CH:8][CH:7]=[C:6]([C:13](=[C:12]([CH3:18])[CH3:11])[CH3:14])[C:3]=1[C:4]#[N:5]

Participants

3

Reactant 2

HCID 98130382-Amino-6-bromobenzonitrileHCID 16217755(3-Methylbut-2-en-2-yl)boronic acid

Product 1

HCID 674000382-Amino-6-(3-methylbut-2-en-2-yl)benzonitrile

Procedure

Prepared as in Example 1a from 2-amino-6-bromobenzonitrile and 3-Methyl-2-buten-2-ylboronic acid as an orange oil. MS 187 (MH+).

Sources & evidence

ORD record
ord-b8900a184eaf4d0e937bb6ba2b223f29
Source dataset
uspto-grants-2014_01
Patent number
US08633186B2

Reaction notes

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