HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Amino-6-fluorobenzonitrile → 3-(3-amino-2-cyanophenoxy)-N-(2-(benzyloxy)ethyl)-2,2-dimethylpropanamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Amino-6-fluorobenzonitrile | HCID 522659 | — |
| Reactant | N-(2-(benzyloxy)ethyl)-3-hydroxy-2,2-dimethylpropanamide | HCID 66745964 | — |
| Product | 3-(3-amino-2-cyanophenoxy)-N-(2-(benzyloxy)ethyl)-2,2-dimethylpropanamide | HCID 66746036 | 82% |
Reaction Steps
Prepared as in Example 215b (Method B) from N-(2-(benzyloxy)ethyl)-3-hydroxy-2,2-dimethylpropanamide (Example 218c) and 2-amino-6-fluorobenzonitrile in 82% yield. MS 368 (MH+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08633186B2 |
| Source dataset | uspto-grants-2014_01 |
| ORD ID | ord-e144d20500554287a250ff3b8efbc516 |
| Source note | uspto-grants-2014_01 |