Acetyl chloride → 1-(2-Cyano-3-nitrophenoxy)-2,2,4-trimethylpentan-3-yl acetate

HRID 471738Notes

Reaction equation

[OH:1][CH:2]([CH:19]([CH3:21])[CH3:20])[C:3]([CH3:18])([CH3:17])[CH2:4][O:5][C:6]1[CH:13]=[CH:12][CH:11]=[C:10]([N+:14]([O-:16])=[O:15])[C:7]=1[C:8]#[N:9].[C:22](Cl)(=[O:24])[CH3:23]>>[C:22]([O:1][CH:2]([CH:19]([CH3:21])[CH3:20])[C:3]([CH3:17])([CH3:18])[CH2:4][O:5][C:6]1[CH:13]=[CH:12][CH:11]=[C:10]([N+:14]([O-:16])=[O:15])[C:7]=1[C:8]#[N:9])(=[O:24])[CH3:23]

Participants

Reactant 2

HCID 6367Acetyl chloride

HCID 673992382-(3-Hydroxy-2,2,4-trimethylpentyloxy)-6-nitrobenzonitrile

Product 1

HCID 673999391-(2-Cyano-3-nitrophenoxy)-2,2,4-trimethylpentan-3-yl acetateYield 50%

Procedure

Prepared as in Example 231c from 2-(3-hydroxy-2,2,4-trimethylpentyloxy)-6-nitrobenzonitrile (Example 243d) and acetyl chloride in 50% yield. MS 335 (MH+).

Sources & evidence

ORD record: ord-e20b380347ce4419984413fa016359e1
Source dataset: uspto-grants-2014_01
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08633186B2

Reaction notes

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