Chlorosulfamic acid → HCID 67397292, compound

HRID 471745Notes

Reaction equation

HRID 471745 reaction equation
[NH2:1][C:2]1[CH:9]=[CH:8][CH:7]=[C:6]([O:10][CH2:11][CH2:12][O:13][CH2:14][CH2:15][O:16][CH2:17][CH3:18])[C:3]=1[C:4]#[N:5].[S:19](Cl)(=[O:22])(=[O:21])[NH2:20]>>[S:19]([NH:1][C:2]1[CH:9]=[CH:8][CH:7]=[C:6]([O:10][CH2:11][CH2:12][O:13][CH2:14][CH2:15][O:16][CH2:17][CH3:18])[C:3]=1[C:4]#[N:5])(=[O:22])(=[O:21])[NH2:20]

Participants

3

Reactant 2

HCID 24499Chlorosulfamic acidHCID 67399827HCID 67399827, compound

Product 1

HCID 67397292HCID 67397292, compoundYield 69%

Procedure

Prepared as in Example 215a from 2-amino-6-(2-(2-ethoxyethoxy)ethoxy)benzonitrile (Example 250b) and sulfamoyl chloride in 69% yield. MS 330 (MH+).

Sources & evidence

ORD record
ord-5bfad8d9090d47f1ba981083758651a5
Source dataset
uspto-grants-2014_01
Patent number
US08633186B2

Reaction notes

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