Chlorosulfamic acid → HCID 67399845, compound

HRID 471747Notes

Reaction equation

HRID 471747 reaction equation
[NH2:1][C:2]1[CH:9]=[CH:8][CH:7]=[C:6]([O:10][CH:11]2[CH2:15][CH2:14][CH:13]([CH3:16])[CH2:12]2)[C:3]=1[C:4]#[N:5].[S:17](Cl)(=[O:20])(=[O:19])[NH2:18]>>[S:17]([NH:1][C:2]1[CH:9]=[CH:8][CH:7]=[C:6]([O:10][CH:11]2[CH2:15][CH2:14][CH:13]([CH3:16])[CH2:12]2)[C:3]=1[C:4]#[N:5])(=[O:20])(=[O:19])[NH2:18]

Participants

3

Reactant 2

HCID 24499Chlorosulfamic acidHCID 67399909HCID 67399909, compound

Product 1

HCID 67399845HCID 67399845, compoundYield 52%

Procedure

Prepared as in Example 215a from 2-amino-6-(3-methylcyclopentyloxy)benzonitrile (Example 251b) and sulfamoyl chloride in 52% yield. MS 296 (MH+).

Sources & evidence

ORD record
ord-dcee0fbc246a4dc7b523e361b740b52a
Source dataset
uspto-grants-2014_01
Patent number
US08633186B2

Reaction notes

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