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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 471749Generated: October 28, 2026

Chlorosulfamic acid → 1-(3-(3-Sulfamoylamino-2-cyanophenoxy)-2,2-dimethylpropyl)-3-(4-methoxybenzyl)urea

https://huagongshe.com/reaction/471749

Reaction equation

Participants

RoleNameHCIDCharge
ReactantChlorosulfamic acidHCID 24499—
Reactant1-(3-(3-Amino-2-cyanophenoxy)-2,2-dimethylpropyl)-3-(4-methoxybenzyl)ureaHCID 66746233—
Product1-(3-(3-Sulfamoylamino-2-cyanophenoxy)-2,2-dimethylpropyl)-3-(4-methoxybenzyl)ureaHCID 66747379100%

Reaction Steps

Prepared as in Example 215a from 1-(3-(3-amino-2-cyanophenoxy)-2,2-dimethylpropyl)-3-(4-methoxybenzyl)urea (Example 252b) and sulfamoyl chloride in 100% yield. MS 462 (MH+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08633186B2
Source datasetuspto-grants-2014_01
ORD IDord-708e7ffb0e6445159c0d15df2042535d
Source noteuspto-grants-2014_01