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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 471758Generated: November 3, 2026

1-(2-Hydroxyethyl)-2-pyrrolidinone → 2-Nitro-6-(2-(2-oxopyrrolidin-1-yl)ethoxy)benzonitrile

https://huagongshe.com/reaction/471758

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(2-Hydroxyethyl)-2-pyrrolidinoneHCID 76980—
ReactantDinitrobenzonitrileHCID 520718—
Product2-Nitro-6-(2-(2-oxopyrrolidin-1-yl)ethoxy)benzonitrileHCID 6674673374%

Reaction Steps

Prepared as in Example 166d from 1-(2-hydroxyethyl)pyrrolidin-2-one and 2,6-dinitrobenzonitrile in 74% yield. MS 276 (MH+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08633186B2
Source datasetuspto-grants-2014_01
ORD IDord-0b2e36be0287428f8d9bb1e446aaf708
Source noteuspto-grants-2014_01