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HRID471786

反应详情

EQUATION

反应方程式

HRID 471786 的结构方程式

REACTANTS

反应物

2
结构：NS(=O)(=O)Cl
HCID24499

Amidosulfonic acid chloride

H2ClNO2S

结构：CC(C)(C)OC(=O)NCCCCCCOc1cccc(N)c1C#N
HCID66746101

未命名化合物

PRODUCTS

生成物

1
结构：CC(C)(C)OC(=O)NCCCCCCOc1cccc2c1C(N)=NS(=O)(=O)N2
HCID66746882

未命名化合物

收率 59.5%

PROCEDURE

实验过程

Prepared as in Example 274 from tert-butyl 6-(3-amino-2-cyanophenoxy)hexylcarbamate (Example 281a) and sulfamoyl chloride in 59.5% yield. 1H NMR (400 MHz, DMSO-d6) δ 1.274 (m, 2H), 1.339 (s, 9H), 1.361 (m, 4H), 1.779 (pentet, J=7 Hz, 2H), 2.878 (q, J=6 Hz, 2H), 4.122 (t, J=6 Hz, 2H), 6.580 (d, J=8 Hz, 1H), 6.722 (d, J=8 Hz, 1H), 6.75 (br t, J=6 Hz, 1H), 7.428 (t, J=8 Hz, 1H), 7.798 (br. s, 1H), 8.323 (br. s, 1H), 10.921 (s, 1H). MS 413 (MH+).