Sodium Hydroxide → HCID 58269960, compound

Participants

Reaction Steps

The titled compound is prepared from 7-chloro-5-(2,6-diethyl-phenyl)-3,4-dimethyl-1H-pyrrolo[2,3-c]pyridine (Example 7) by catalytic hydrogenation (10% Pd on carbon in MeOH with addition of 15% of 10 M NaOH) at 50 psi. 1H NMR: (CDCl3) 10.2 (1H, br), 8.85 (1H, s), 7.3 (1H, t, J=7.8 Hz), 7.20 (2H, d, J=7.8 Hz), 6.7 (1H, s), 2.50 (3H, s), 2.36 (3H, s), 2.29 (4H, q, J=7.0 Hz), 1.04 (6H, t, J=7.0 Hz).

Provenance & Evidence