HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 67152644, compound → HCID 67152403, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 67152644 | HCID 67152644 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 67152403 | HCID 67152403 | — |
Reaction Steps
A mixture of (2-[1-[5-(2,6-diethyl-phenyl)-1-(4-isopropyl-phenyl)-1H-pyrrolo[2,3-c]pyridin-3-yl]-meth-(E)-ylidene]-pentanoic acid ethyl ester (120 mg, 0.23 mmol), 10% Pd/C (20 mg), and EtOH (4 mL) is stirred under hydrogen (1 atm) for 18 h at room temperature. The mixture is filtered over celite and concentrated under reduced pressure to afford 2-[5-(2,6-diethyl-phenyl)-1-(4-isopropyl-phenyl)-1H-pyrrolo[2,3-c]pyridin-3-ylmethyl]-pentanoic acid ethyl ester as colorless oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08633193B2 |
| Source dataset | uspto-grants-2014_01 |
| ORD ID | ord-437bcbbe2ad9476aab80ea0bfaef83c3 |
| Source note | uspto-grants-2014_01 |