HRID472311

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：CN(C)S(=O)(=O)c1ccc(B2OC(C)(C)C(C)(C)O2)cc1

HCID3868489

N,N-Dimethyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzene-1-sulfonamide

C14H22BNO4S

HCID46864069

8-Bromo[1,2,4]triazolo[1,5-a]pyridin-2-amine

C6H5BrN4

PRODUCTS

生成物

结构：CN(C)S(=O)(=O)c1ccc(-c2cccn3nc(N)nc23)cc1

HCID67481505

未命名化合物

PROCEDURE

实验过程

4-(2-Amino-[1,2,4]triazolo[1,5-a]pyridin-8-yl)-N,N-dimethyl-benzenesulfonamide was prepared from 8-bromo-[1,2,4]triazolo[1,5-a]pyridin-2-ylamine (150.0 mg, 0.7041 mmol) and N,N-dimethyl-4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-benzenesulfonamide (210.0 mg, 0.6748 mmol) in a manner analogous to Step 2c. The reaction product was isolated as a tan solid (0.074 g, 34%). MP=188-190° C. 1H NMR (400 MHz, (D3C)2SO, δ, ppm): 8.63 (d, J=6.4 Hz, 1H), 8.38 (d, J=8.2 Hz, 2H), 7.88-7.82 (m, 3H), 7.03 (t, J=6.8 Hz, 1H), 6.21 (br s, 2H), 2.66 (s, 6H). MS=318 (MH)+.