HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-Bromo-[1,2,4]triazolo[1,5-a]pyridin-2-amine → 5-[4-[(1,1-Dioxo-1,4-thiazinan-4-yl)methyl]phenyl]-[1,2,4]triazolo[1,5-a]pyridin-2-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-Bromo-[1,2,4]triazolo[1,5-a]pyridin-2-amine | HCID 25215939 | — |
| Reactant | (4-((1,1-Dioxidothiomorpholino)methyl)phenyl)boronic acid | HCID 54970580 | — |
| Product | 5-[4-[(1,1-Dioxo-1,4-thiazinan-4-yl)methyl]phenyl]-[1,2,4]triazolo[1,5-a]pyridin-2-amine | HCID 67479440 | — |
Reaction Steps
5-{-4-[(1,1-dioxidothiomorpholin-4-yl)methyl]phenyl}[1,2,4]triazolo[1,5-a]pyridin-2-amine was prepared from 5-bromo-[1,2,4]triazolo[1,5-a]pyridin-2-ylamine and 4-[(4-boronophenyl)methyl]-thiomorpholine 1,1-dioxide in a manner analogous to Step 2c. The reaction product was taken on to the next step.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08633173B2 |
| Source dataset | uspto-grants-2014_01 |
| ORD ID | ord-042a536bb51f4d9ca93476251e8038f5 |
| Source note | uspto-grants-2014_01 |