[1-(4-Methylphenyl)-1H-pyrazol-4-yl]boronic acid → HCID 67481369, compound

HRID 472564Notes

Reaction equation

HRID 472564 reaction equation
Br[C:2]1[C:3]2[N:4]([N:8]=[C:9]([Cl:11])[N:10]=2)[CH:5]=[CH:6][CH:7]=1.[C:12]1([CH3:26])[CH:17]=[CH:16][C:15]([N:18]2[CH:22]=[C:21](B(O)O)[CH:20]=[N:19]2)=[CH:14][CH:13]=1>>[Cl:11][C:9]1[N:10]=[C:3]2[C:2]([C:21]3[CH:20]=[N:19][N:18]([C:15]4[CH:16]=[CH:17][C:12]([CH3:26])=[CH:13][CH:14]=4)[CH:22]=3)=[CH:7][CH:6]=[CH:5][N:4]2[N:8]=1

Participants

3

Reactant 2

HCID 46738688[1-(4-Methylphenyl)-1H-pyrazol-4-yl]boronic acidHCID 674813708-Bromo-2-chloro-[1,2,4]triazolo[1,5-a]pyridine

Product 1

HCID 67481369HCID 67481369, compound

Procedure

2-Chloro-8-(1-p-tolyl-1H-pyrazol-4-yl)-[1,2,4]triazolo[1,5-a]pyridine was prepared from 8-bromo-2-chloro-[1,2,4]triazolo[1,5-a]pyridine and 1-p-tolyl-pyrazole-4-boronic acid in a manner analogous to Example 2c (0.40 g, 68%).

Sources & evidence

ORD record
ord-9196eff16f2a4203bfd8d623cd1a6544
Source dataset
uspto-grants-2014_01
Patent number
US08633173B2

Reaction notes

Loading…