Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 472570Generated: October 30, 2026

B-[3-(2-Methylpropoxy)phenyl]boronic acid → 2-Chloro-8-(3-isobutoxy-phenyl)-[1,2,4]triazolo[1,5-a]pyridine

https://huagongshe.com/reaction/472570

Reaction equation

Participants

RoleNameHCIDCharge
ReactantB-[3-(2-Methylpropoxy)phenyl]boronic acidHCID 16217826—
Reactant8-Bromo-2-chloro-[1,2,4]triazolo[1,5-a]pyridineHCID 67481370—
Product2-Chloro-8-(3-isobutoxy-phenyl)-[1,2,4]triazolo[1,5-a]pyridineHCID 67479150—

Reaction Steps

2-Chloro-8-(3-isobutoxy-phenyl)-[1,2,4]triazolo[1,5-a]pyridine was prepared from 8-bromo-2-chloro-[1,2,4]triazolo[1,5-a]pyridine and 3-isobutoxyphenylboronic acid in a manner analogous to Example 2c (0.39 g, 60%). MS=302 (MH)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08633173B2
Source datasetuspto-grants-2014_01
ORD IDord-8ff329d9798847ca8d0e65a7da3e0ef5
Source noteuspto-grants-2014_01