HCID 67479073, compound → HCID 67478801, compound

HRID 472571Notes

Reaction equation

HRID 472571 reaction equation
Br[C:2]1[C:3]2[N:4]([N:8]=[C:9]([Cl:11])[N:10]=2)[CH:5]=[CH:6][CH:7]=1.[CH2:12]([O:16][C:17]1[CH:22]=[C:21]([CH3:23])[CH:20]=[CH:19][C:18]=1B(O)O)[CH:13]([CH3:15])[CH3:14]>>[Cl:11][C:9]1[N:10]=[C:3]2[C:2]([C:18]3[CH:19]=[CH:20][C:21]([CH3:23])=[CH:22][C:17]=3[O:16][CH2:12][CH:13]([CH3:15])[CH3:14])=[CH:7][CH:6]=[CH:5][N:4]2[N:8]=1

Participants

3

Reactant 2

HCID 67479073HCID 67479073, compoundHCID 674813708-Bromo-2-chloro-[1,2,4]triazolo[1,5-a]pyridine

Product 1

HCID 67478801HCID 67478801, compound

Procedure

2-Chloro-8-(2-isobutoxy-4-methylphenyl)-[1,2,4]triazolo[1,5-a]pyridine was prepared from 8-bromo-2-chloro-[1,2,4]triazolo[1,5-a]pyridine and 2-isobutoxy-4-methylphenylboronic acid in a manner analogous to Example 2c (0.48 g, 71%). MS=316 (MH)+.

Sources & evidence

ORD record
ord-38fb511f8c8149e19d576362e5ef7493
Source dataset
uspto-grants-2014_01
Patent number
US08633173B2

Reaction notes

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