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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 472576Generated: October 30, 2026

B-(5-Chloro-2-propoxyphenyl)boronic acid → 2-Chloro-8-(5-chloro-2-propoxy-phenyl)-[1,2,4]triazolo[1,5-a]pyridine

https://huagongshe.com/reaction/472576

Reaction equation

Participants

RoleNameHCIDCharge
ReactantB-(5-Chloro-2-propoxyphenyl)boronic acidHCID 16217680—
Reactant8-Bromo-2-chloro-[1,2,4]triazolo[1,5-a]pyridineHCID 67481370—
Product2-Chloro-8-(5-chloro-2-propoxy-phenyl)-[1,2,4]triazolo[1,5-a]pyridineHCID 67479095—

Reaction Steps

2-Chloro-8-(5-chloro-2-propoxy-phenyl)-[1,2,4]triazolo[1,5-a]pyridine was prepared from 8-bromo-2-chloro-[1,2,4]triazolo[1,5-a]pyridine and 5-chloro-2-propoxyphenylboronic acid in a manner analogous to Example 2c (0.46 g, 66%). MS=323 (MH)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08633173B2
Source datasetuspto-grants-2014_01
ORD IDord-bd40a282dc174c5683b7b4164d128c4c
Source noteuspto-grants-2014_01