1-Naphthoic acid → HCID 66660797, compound

HRID 472788Notes

Reaction equation

HRID 472788 reaction equation
[OH:1][CH:2]([C:6]1[CH:7]=[C:8]2[C:13](=[CH:14][CH:15]=1)[C:12]([C:16]([O:18]C)=[O:17])=[CH:11][CH:10]=[CH:9]2)[CH2:3][CH2:4][CH3:5].C1(C(O)=O)C2C(=CC=CC=2)C=CC=1>>[OH:1][CH:2]([C:6]1[CH:7]=[C:8]2[C:13](=[CH:14][CH:15]=1)[C:12]([C:16]([OH:18])=[O:17])=[CH:11][CH:10]=[CH:9]2)[CH2:3][CH2:4][CH3:5]

Participants

3

Reactant 2

HCID 68471-Naphthoic acidHCID 66660674HCID 66660674, compound

Product 1

HCID 66660797HCID 66660797, compound

Procedure

In accordance with the procedure of Example 1, step 4, methyl 6-(1-hydroxybutyl)-1-naphthoate (14 mg, 0.05 mmol) was converted into 13 mg (98%) of 641-hydroxybutyl)-1-naphthoic acid.

Sources & evidence

ORD record
ord-b50b6ee5ad664d58a09dbc2ab1e80d12
Source dataset
uspto-grants-2014_01
Patent number
US08633220B2

Reaction notes

Loading…