HuagongsheHuagongshe Chemistry Print Report · For research reference only
Formic Acid → 8-(Benzyloxy)imidazo[1,5-a]pyridine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Formic Acid | HCID 284 | — |
| Reactant | Phosphorus oxychloride | HCID 24813 | — |
| Reactant | HCID 12074949 | HCID 12074949 | — |
| Product | 8-(Benzyloxy)imidazo[1,5-a]pyridine | HCID 45489690 | — |
Reaction Steps
This compound is prepared according to the same procedure as in preparation II (stage C) from 2.8 g (13.25 mmol) of 1-[3-(benzyloxy)pyridin-2-yl]methanamine [described in Inorg. Chem., (2003), 42(14), 4401] by formylation with formic acid and then cyclization by reaction with phosphoryl chloride. 1.74 g of a brown oil are obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08633216B2 |
| Source dataset | uspto-grants-2014_01 |
| ORD ID | ord-1f5568f766304aa78c6458f8d07aab3a |
| Source note | uspto-grants-2014_01 |