HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
1,8-Diazabicyclo(5.4.0)undec-7-ene → 1-Chloro-4-[(3-chloro-4-methylbenzyl)amino]-6-phthalazinecarbonitrile
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 1,8-Diazabicyclo(5.4.0)undec-7-ene | HCID 81184 | — |
| Edukt | Benzenemethanamine, 3-chloro-4-methyl- | HCID 106225 | — |
| Edukt | 1,4-Dichlorophthalazine-6-carbonitrile | HCID 10656738 | — |
| Lösungsmittel | N-methyl-2-pyrrolidone | HCID 13387 | — |
| Produkt | 1-Chloro-4-[(3-chloro-4-methylbenzyl)amino]-6-phthalazinecarbonitrile | HCID 18374619 | — |
Reaktionsschritte
1,4-Dichlorophthalazine-6-carbonitrile and 3-chloro-4-methylbenzylamine were stirred at room temperature in 1-methyl-2-pyrrolidinone in the presence of DBU, whereby the title compound was obtained as a less polar compound.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US06699870B2 |
| Quelldatensatz | uspto-grants-2004_03 |
| ORD ID | ord-6bbd4910440449faafa0c8e9303aefc7 |
| Quellennotiz | uspto-grants-2004_03 |