反应详情

A solution of the above alcohol (1.891 g, 5.61 mmol) in dichloromethane (35 ml) was added with manganese dioxide (3.905 g, 44.9 mmol), and the mixture was refluxed by heating for 2 hours with stirring. The reaction mixture was filtered through Cerite under reduced pressure, and Cerite was washed with chloroform. The solvent was evaporated, and then the residue was recrystallized to obtain the title compound (1.802 g, 96%) as colorless prisms.

1. temperaturethe mixture was refluxed
2. temperatureby heating for 2 hours
3. filtrationThe reaction mixture was filtered through Cerite under reduced pressure, and Cerite
4. washwas washed with chloroform
5. customThe solvent was evaporated
6. customthe residue was recrystallized