HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-[2-(3-Chlorophenyl)-vinyl]-4-methoxybenzoic acid → 2-[2-(3-Chlorophenyl)-ethyl]-4-methoxybenzoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-[2-(3-Chlorophenyl)-vinyl]-4-methoxybenzoic acid | HCID 67497207 | — |
| Reactant | HCID 178418361 | HCID 178418361 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Product | 2-[2-(3-Chlorophenyl)-ethyl]-4-methoxybenzoic acid | HCID 67359984 | — |
Reaction Steps
For the synthesis of the title compound, 6.0 g of 2-[2-(3-chlorophenyl)-vinyl]-4-methoxybenzoic acid, 0.6 g of Pd/C (10%) and 41 of hydrogen are employed in method J (variant 2). The solvent mixture comprises 75 ml of acetonitrile, 75 ml of ethyl acetate and 20 ml of methanol. C16H15ClO3(Mr=290.75)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08633312B2 |
| Source dataset | uspto-grants-2014_01 |
| ORD ID | ord-dd993dd3ec744765a43eec69a6271931 |
| Source note | uspto-grants-2014_01 |