HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-[2-(3-Chlorophenyl)-vinyl]-3-methoxybenzoic acid → [2-(3-Chlorophenyl)-ethyl]-3-methoxybenzoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-[2-(3-Chlorophenyl)-vinyl]-3-methoxybenzoic acid | HCID 67497995 | — |
| Reactant | HCID 178418361 | HCID 178418361 | — |
| Catalyst | Pd barium sulfate | HCID 16218511 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | [2-(3-Chlorophenyl)-ethyl]-3-methoxybenzoic acid | HCID 67360277 | 87% |
Reaction Steps
For the synthesis of the title compound, 6.0 g of 2-[2-(3-chlorophenyl)-vinyl]-3-methoxybenzoic acid, 0.6 g of Pd/BaSO4 (5%), 4 l of hydrogen and 150 ml of methanol are employed in method J (variant 1). Yield: 87%; m.p.: 91° C.; C16H15ClO3 (Mr=290.75)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08633312B2 |
| Source dataset | uspto-grants-2014_01 |
| ORD ID | ord-d0edb5ebad7e4f33b0f3fe48f6a5cbe6 |
| Source note | uspto-grants-2014_01 |