HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thionyl Chloride → HCID 67360944, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | Aluminum(III) Chloride | HCID 6451240 | — |
| Reactant | [2-(3-Chlorophenyl)-ethyl]-3-methoxybenzoic acid | HCID 67360277 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 67360944 | HCID 67360944 | — |
Reaction Steps
For the synthesis of the title compound, 16.6 g (0.057 mol) of [2-(3-chlorophenyl)-ethyl]-3-methoxybenzoic acid, 7.25 g (0.06 mol) of SOCl2, 250 ml of methylene chloride and 10 g of AlCl3 are employed in method K. Purification is carried out by column chromatography (flash; SiO2; hexane 90%/ethyl acetate 10%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08633312B2 |
| Source dataset | uspto-grants-2014_01 |
| ORD ID | ord-928e536e7ae8490bb6d229a856b1915d |
| Source note | uspto-grants-2014_01 |