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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 473474Generated: October 30, 2026

p-Toluenesulfonic acid monohydrate → HCID 45280693, compound

https://huagongshe.com/reaction/473474

Reaction equation

Participants

RoleNameHCIDCharge
Reactantp-Toluenesulfonic acid monohydrateHCID 521998—
ReactantHCID 45280692HCID 45280692—
SolventMethanolHCID 887—
SolventWaterHCID 962—
ProductHCID 45280693HCID 4528069340%

Reaction Steps

For the synthesis of the title compound, 0.10 g (0.225 mmol) of (S)-8-(2-aminophenylamino)-1-(2,2-dimethyl-[1,3]dioxolan-4-ylmethoxy)-10,11-dihydrodibenzo[a,d]cyclohepten-5-one and 0.0537 g (0.282 mmol) of p-toluenesulfonic acid monohydrate in 6 ml of methanol and 1.5 ml of water are reacted by method N. C24H24N2O4 (Mr=404.47); yield: 40%

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08633312B2
Source datasetuspto-grants-2014_01
ORD IDord-ee4d70c7784f448baf83df189dc50caa
Source noteuspto-grants-2014_01