HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Carbonate → 8-Chloro-1-(2-morpholin-4-yl-ethoxy)-10,11-dihydrodibenzo[a,d]cyclohepten-5-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | Morpholine, 4-(2-chloroethyl)-, hydrochloride (1:1) | HCID 77210 | — |
| Reactant | HCID 67359866 | HCID 67359866 | — |
| Solvent | Acetonitrile | HCID 6342 | — |
| Product | 8-Chloro-1-(2-morpholin-4-yl-ethoxy)-10,11-dihydrodibenzo[a,d]cyclohepten-5-one | HCID 67360818 | — |
Reaction Steps
For the synthesis of the title compound, 0.44 g (1.69 mmol) of 8-chloro-1-hydroxy-10,11-dihydrodibenzo[a,d]cyclohepten-5-one, 0.345 g (1.86 mmol) of 4-(2-chloroethyl)morpholine hydrochloride and 0.93 g (6.75 mmol) of K2CO3 in 15 ml of acetonitrile are reacted by method Q. C21H21ClNO3 (Mr=371.87); GC 29.7 min
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08633312B2 |
| Source dataset | uspto-grants-2014_01 |
| ORD ID | ord-6f24dba4987b468f8511415bc5111a00 |
| Source note | uspto-grants-2014_01 |