HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dichloromethane → N,N-bis(2-chloroethyl)methyl ammonium hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dichloromethane | HCID 6344 | — |
| Reactant | N-Methyldiethanolamine | HCID 7767 | — |
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Product | N,N-bis(2-chloroethyl)methyl ammonium hydrochloride | HCID 71676372 | 85% |
Reaction Steps
A solution of N-methyldiethanolamine (3 g, 25 mmol) in CH2Cl2 (5 mL) was slowly added dropwise to thionyl chloride (10 mL) in ice-water bath, then stirred at r. t. for 2 days. After evaporated, the residue was dispersed with CH3 CN/Et2O, then was filtered to give N,N-bis(2-chloroethyl)methyl ammonium hydrochloride (4.1 g, 85%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08637490B2 |
| Source dataset | uspto-grants-2014_01 |
| ORD ID | ord-d0c466cc3b5a4fa790d682c2b5515d42 |
| Source note | uspto-grants-2014_01 |