3-(3,6-dihydro-2H-pyran-4-yl)-2-fluoropyridine → 2-Fluoro-3-(tetrahydro-2H-pyran-4-yl)pyridine

Participants

Reaction Steps

To a rbf was added 3-(3,6-dihydro-2H-pyran-4-yl)-2-fluoropyridine (2.1320 g, 11.90 mmol) and palladium hydroxide (0.835 g, 1.190 mmol) in EtOAc (39.7 mL). The rbf was flushed with argon and then placed under vacuum three times. A hydrogen balloon was then attached to the reaction. Upon completion, the reaction was filtered through celite and concentrated. MS (ESI, pos. ion) m/z: 182.1.

Provenance & Evidence