反应详情

A solution of (4-bromo-pyridin-2-yl)-hydrazine (0.50 g) in formic acid (0.50 mL) is stirred at reflux temperature overnight. After cooling to room temperature, the solution was concentrated under reduced pressure. Water was added to the residue and the resulting mixture was extracted with ethyl acetate. The combined organic extracts were washed with brine, dried (MgSO4), and concentrated to give the title compound.

1. temperatureat reflux temperature overnight
2. concentrationthe solution was concentrated under reduced pressure
3. additionWater was added to the residue
4. extractionthe resulting mixture was extracted with ethyl acetate
5. washThe combined organic extracts were washed with brine
6. dry with materialdried (MgSO4)
7. concentrationconcentrated