HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetonitrile → 6-Chloro-4-(3-bromophenyl)-1,2,3,4-tetrahydroquinoline-2-carboxylic acid ethyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetonitrile | HCID 6342 | — |
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | 4-Chloroaniline | HCID 7812 | — |
| Reactant | 3-Bromostyrene | HCID 74870 | — |
| Product | 6-Chloro-4-(3-bromophenyl)-1,2,3,4-tetrahydroquinoline-2-carboxylic acid ethyl ester | HCID 10222282 | — |
Reaction Steps
Compound 55 was prepared by the basic process from 5.0 mmol 4-chloroaniline, 5.5 mmol elhylglyoxalate solution (50% toluene), 15.0 mmol 3-bromostyrene and 5.0 mmol trifluoroacetic acid in 30.0 ml acetonitrile.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06699877B2 |
| Source dataset | uspto-grants-2004_03 |
| ORD ID | ord-96c520df9b554f7b9860e63555736e91 |
| Source note | uspto-grants-2004_03 |