HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Cyclooctene → 2-Trifluoromethoxy-5,6,6a,7,8,9,10,11,12,12a-decahydro-5-aza-cycloocta-[a]naphthalene-6-carboxylic acid ethyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Cyclooctene | HCID 13609 | — |
| Reactant | Ethyl oxoacetate | HCID 70211 | — |
| Reactant | 4-(Trifluoromethoxy)aniline | HCID 600848 | — |
| Product | 2-Trifluoromethoxy-5,6,6a,7,8,9,10,11,12,12a-decahydro-5-aza-cycloocta-[a]naphthalene-6-carboxylic acid ethyl ester | HCID 10133797 | — |
Reaction Steps
Compound 76 was prepared from 4-(trifluoromethoxy)-aniline, glyoxylic acid ethyl ester and cyclooctene by the automated process.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06699877B2 |
| Source dataset | uspto-grants-2004_03 |
| ORD ID | ord-f65ef558ff1b43d8b187200c04483bf7 |
| Source note | uspto-grants-2004_03 |