HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ether hydrochloride → HCID 66762688, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ether hydrochloride | HCID 10953452 | — |
| Reactant | HCID 66763737 | HCID 66763737 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 66762688 | HCID 66762688 | 97% |
Reaction Steps
The title compound was prepared as light yellow solid in 97% yield by treating tert-butyl [3-({[8-(aminocarbonyl)quinazolin-4-yl]amino}methyl)phenyl]carbamate with 2N HCl/ether in DCM overnight. The precipitate was filtered, washed with ether and dried. Mass: M+H+: 294.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08637532B2 |
| Source dataset | uspto-grants-2014_01 |
| ORD ID | ord-e32f8d58d7fd47388ca55b1210e5f1d6 |
| Source note | uspto-grants-2014_01 |