HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 66763896, compound → HCID 66763097, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 66763896 | HCID 66763896 | — |
| Solvent | Hydrogen Bromide | HCID 260 | — |
| Product | HCID 66763097 | HCID 66763097 | 13% |
Reaction Steps
In a 20 mL scintillation vial 6-Benzyloxy-4-[1-(3-chloro-phenyl)-2-dimethylamino-ethylamino]-quinazoline-8-carboxylic acid amide was taken in 5 ml of aqueous HBr solution and stirred at room temperature for 2 h. Reaction was concentrated and dissolved in methanol and the crude was purified on preparative HPLC to give the product, (7.0 mg, 13% yield). LCMS (ESI) 386 (M+H)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08637532B2 |
| Source dataset | uspto-grants-2014_01 |
| ORD ID | ord-ed62dc604cdb4f8d8621a5cf02df7f69 |
| Source note | uspto-grants-2014_01 |