2-Chlorobenzothiazole → 4-[3-(Benzothiazol-2-ylamino)-benzylamino]-quinazoline-8-carboxylic acid amide

HRID 474439Notes

Reaction equation

HRID 474439 reaction equation
Cl.[NH2:2][C:3]1[CH:4]=[C:5]([CH:21]=[CH:22][CH:23]=1)[CH2:6][NH:7][C:8]1[C:17]2[C:12](=[C:13]([C:18]([NH2:20])=[O:19])[CH:14]=[CH:15][CH:16]=2)[N:11]=[CH:10][N:9]=1.Cl[C:25]1[S:26][C:27]2[CH:33]=[CH:32][CH:31]=[CH:30][C:28]=2[N:29]=1>>[S:26]1[C:27]2[CH:33]=[CH:32][CH:31]=[CH:30][C:28]=2[N:29]=[C:25]1[NH:2][C:3]1[CH:4]=[C:5]([CH:21]=[CH:22][CH:23]=1)[CH2:6][NH:7][C:8]1[C:17]2[C:12](=[C:13]([C:18]([NH2:20])=[O:19])[CH:14]=[CH:15][CH:16]=2)[N:11]=[CH:10][N:9]=1

Participants

3

Reactant 2

HCID 119872-ChlorobenzothiazoleHCID 667633584-(3-Amino-benzylamino)-quinazoline-8-carboxylic acid amide hydrochloride

Product 1

HCID 770143994-[3-(Benzothiazol-2-ylamino)-benzylamino]-quinazoline-8-carboxylic acid amide

Procedure

The title compound was prepared according to Example 684 starting 4-(3-Amino-benzylamino)-quinazoline-8-carboxylic acid amide hydrochloride and 2-Chloro-benzothiazole:

Sources & evidence

ORD record
ord-9234951448bd4b22a6aefe1070c2e0ee
Source dataset
uspto-grants-2014_01
Patent number
US08637532B2

Reaction notes

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