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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 474445Generated: October 29, 2026

Hydrochloric Acid → HCID 77014393, compound

https://huagongshe.com/reaction/474445

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantHCID 86662388HCID 86662388—
Solvent1,4-DioxaneHCID 31275—
ProductHCID 77014393HCID 77014393—

Reaction Steps

64 mg (0.12 mmol) of (4-{3-[(8-Carbamoyl-quinazolin-4-ylamino)-methyl]-phenylcarbamoyl}-thiazol-2-yl)-carbamic acid tert-butyl ester were dissolved in 1.0 ml dioxane and 620 μl 4 N HCl in dioxane were added. The mixture was stirred overnight and evaporated to dryness.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08637532B2
Source datasetuspto-grants-2014_01
ORD IDord-cf657172e7d942efaedd1ae481f3633b
Source noteuspto-grants-2014_01