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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 474452Generated: October 30, 2026

Hydrochloric Acid → HCID 66763954, compound

https://huagongshe.com/reaction/474452

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantHCID 66762706HCID 66762706—
Solvent1,4-DioxaneHCID 31275—
ProductHCID 66763954HCID 66763954—

Reaction Steps

37 mg (0.56 mmol) 3-{3-[(8-Carbamoyl-quinazolin-4-ylamino)-methyl]-phenylcarbamoyl}-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazine-5-carboxylic acid tert-butyl ester were dissolved in 1.5 ml dioxane and 280 μl 4 N HCl in dioxane were added. The mixture was stirred overnight and evaporated to dryness.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08637532B2
Source datasetuspto-grants-2014_01
ORD IDord-22bcd117b3a14ac9bbb04c4a9b4ab56a
Source noteuspto-grants-2014_01