HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl formate → HCID 67953529, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl formate | HCID 7865 | — |
| Reactant | Methyl 3-(1-methylindol-3-YL)propanoate | HCID 13679809 | — |
| Reactant | Potassium tert-butoxide | HCID 23665647 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 67953529 | HCID 67953529 | — |
Reaction Steps
To the solution of 1-methylindole-3-propionic acid methyl ester (700 mg, 3.22 mmol) and methyl formate (0.397 mL, 6.44 mmol) in THF (20 mL) was added potassium tert-butoxide (723 mg, 6.44 mmol). The mixture was stirred at room temperature for 1 h. concentration in vacuo then afforded the title compound. LCMS: rt=2.81 min, [M+H+]=246
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08637536B2 |
| Source dataset | uspto-grants-2014_01 |
| ORD ID | ord-ba449fb79e3a472db2ce73594008c343 |
| Source note | uspto-grants-2014_01 |