2-(4-(4-Chloro-3-(trifluoromethyl)phenoxy)phenyl)ethanamine → HCID 178494131, Verbindung

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Reaktionsschritte

To the solution of 5-{[2-(methyloxy)-5-pyrimidinyl]methyl}-2-(nitroamino)-4(1H)-pyrimidinone (100 mg, 0.359 mmol) in ethanol (5 mL) was added neat 2-(4-{[4-chloro-3-(trifluoromethyl)-phenyl]oxy}phenyl)ethanamine (189 mg, 0.599 mmol). It was heated with a microwave reactor at 100° C. overnight. Purification via MDAP then afforded the title compound (92 mg, 35.6% yield). LCMS: rt=3.04 min, [M+H+]=532.2

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