2-Bromo-1,3,2-benzodioxaborole → HCID 178517739, compound

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A mixture of 2-{[(4-{[4-chloro-3-(trifluoromethyl)phenyl]oxy}phenyl)methyl]thio}-5-{[2-(methyloxy)-5-pyrimidinyl]methyl}-4(1H)-pyrimidinone and B-bromocatecholborane (357 mg, 1.795 mmol) in DCM (10 mL) was stirred at room temperature for 24 h. Purification via MDAP then afforded the title compound (24 mg, 25.3% yield). LCMS: rt=3.01 min, [M+H+]=521

Provenance & Evidence